Some Astrocytes Appear to Promote Progressive MS
نویسندگان
چکیده
منابع مشابه
Reactive astrocytes secrete lcn2 to promote neuron death.
Glial reaction is a common feature of neurodegenerative diseases. Recent studies have suggested that reactive astrocytes gain neurotoxic properties, but exactly how reactive astrocytes contribute to neurotoxicity remains to be determined. Here, we identify lipocalin 2 (lcn2) as an inducible factor that is secreted by reactive astrocytes and that is selectively toxic to neurons. We show that lcn...
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ژورنال
عنوان ژورنال: Multiple Sclerosis Discovery Forum
سال: 2014
ISSN: 2165-9893
DOI: 10.7493/msdf.10.14497.1